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Breaking News on the Enantioselective Intermolecular Heck Reaction
Author(s) -
Oestreich Martin
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201310585
Subject(s) - enantioselective synthesis , heck reaction , phosphine , intermolecular force , chemistry , organic chemistry , phosphorus , catalysis , combinatorial chemistry , palladium , molecule
Glowing results with less phosphorus: Tremendous progress has been made recently in asymmetric intermolecular Heck chemistry. Previously unprecedented enantioselective Heck–Matsuda reactions have been accomplished, and mixed phosphine/phosphine oxides have been shown to be superior ligands in enantioselective Mizoroki–Heck reactions. All of this was achieved with chiral ligands containing few or even no phosphorus donors (see scheme).