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Selective Palladium‐Catalyzed Aminocarbonylation of Olefins with Aromatic Amines and Nitroarenes
Author(s) -
Fang Xianjie,
Jackstell Ralf,
Beller Matthias
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201308455
Subject(s) - regioselectivity , catalysis , palladium , chemistry , combinatorial chemistry , organic chemistry
Various olefins can be smoothly transformed in the presence of a Pd‐based catalyst system and (hetero)aromatic amines or nitroarenes to synthetically interesting amides in good yields and often with high regioselectivity (see scheme). Combining this atom‐efficient procedure with established functionalizations of the resulting products allows the efficient preparation of quinolines.