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Inside Cover: Chemoselective Oxidative C(CO)C(methyl) Bond Cleavage of Methyl Ketones to Aldehydes Catalyzed by CuI with Molecular Oxygen (Angew. Chem. Int. Ed. 43/2013)
Author(s) -
Zhang Lin,
Bi Xihe,
Guan Xiaoxue,
Li Xingqi,
Liu Qun,
Barry BadruDeen,
Liao Peiqiu
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201308184
Subject(s) - chemistry , catalysis , aldehyde , bond cleavage , oxidative cleavage , cleavage (geology) , oxygen , molecular oxygen , oxidative phosphorylation , medicinal chemistry , copper , photochemistry , organic chemistry , materials science , biochemistry , fracture (geology) , composite material
The selective oxidative cleavage of CC σ‐bonds is a great challenge in chemistry and biology. In their Communication on page 11303 ff., X. Bi, Q. Liu, and co‐workers describe a novel method for the oxidative C(CO)C(α) bond cleavage of ketones that completely terminates at the aldehyde stage. A wide range of aromatic and aliphatic methyl ketones could be transformed into aldehydes with a copper catalyst under an oxygen atmosphere, along with the release of H 2 and CO 2 as the by‐products.