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Copper‐Catalyzed Three‐Component Oxytrifluoromethylation of Alkenes with Sodium Trifluoromethanesulfinate and Hydroxamic Acid
Author(s) -
Jiang XinYi,
Qing FengLing
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201307595
Subject(s) - catalysis , hydroxamic acid , copper , component (thermodynamics) , chemistry , sodium , organic chemistry , physics , thermodynamics
Radical paths : The title reaction of olefins with NaSO 2 CF 3 and N ‐hydroxy‐ N ‐phenylacetamide at room temperature is described for the first time (see scheme). This reaction provides a practical and convenient route to a series of trifluoromethylated alcohols bearing a wide range of functional groups.