Premium
Copper‐Catalyzed Three‐Component Oxytrifluoromethylation of Alkenes with Sodium Trifluoromethanesulfinate and Hydroxamic Acid
Author(s) -
Jiang XinYi,
Qing FengLing
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201307595
Subject(s) - catalysis , hydroxamic acid , copper , component (thermodynamics) , chemistry , sodium , organic chemistry , physics , thermodynamics
Radical paths : The title reaction of olefins with NaSO 2 CF 3 and N ‐hydroxy‐ N ‐phenylacetamide at room temperature is described for the first time (see scheme). This reaction provides a practical and convenient route to a series of trifluoromethylated alcohols bearing a wide range of functional groups.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom