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[3]Dendralene Synthesis: Rhodium(III)‐Catalyzed Alkenyl CH Activation and Coupling Reaction with Allenyl Carbinol Carbonate
Author(s) -
Wang Honggen,
Beiring Bernhard,
Yu DaGang,
Collins Karl D.,
Glorius Frank
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201306754
Subject(s) - rhodium , catalysis , stereoselectivity , chemistry , coupling reaction , carbonate , medicinal chemistry , reaction conditions , functional group , coupling (piping) , combinatorial chemistry , organic chemistry , materials science , metallurgy , polymer
[3]DendrAl(l)ene! A new synthesis of [3]dendralenes is based on a Rh III ‐catalyzed alkenyl CH activation and coupling reaction with allenyl carbinol carbonates (see scheme; DG=directing group). A variety of [3]dendralenes with diverse substitution patterns are accessible with good efficiency. The reaction is highly stereoselective and compatible with different directing groups and numerous functional groups.