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The Winding Road to Pluripotency (Nobel Lecture)
Author(s) -
Yamanaka Shinya
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201306721
Subject(s) - reprogramming , induced pluripotent stem cell , somatic cell , microbiology and biotechnology , biology , regenerative medicine , stem cell , embryonic stem cell , genetics , cell , gene
The forced expression of certain transcription factors can induce pluripotency in somatic cells. This led to the research and development of effective reprogramming techniques for the generation of induced pluripotent stem cells (iPS cells). S. Yamanaka received the 2012 Nobel Prize in Physiology or Medicine for his research in this area.