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Using Monovalent Phosphorus Compounds to Form P–C Bonds
Author(s) -
Ng Yong Xiang,
Mathey Francois
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201306643
Subject(s) - phosphinidene , electrophile , chemistry , phosphine , aryl , phosphorus , medicinal chemistry , electrophilic addition , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , alkyl
User friendly P–C : Electrophilic terminal phosphinidene complexes [RPW(CO) 5 ] react with ArB(OH) 2 to give the corresponding secondary phosphine complexes [{R(Ar)PH}W(CO) 5 ]. This method enables the formation of PC bonds through the combination of a wide array of heterocyclic and aryl boronic acids with various electrophilic phosphinidene complexes. The final products incorporate a PH bond that can be used for further transformations.