Premium
CH Bond Functionalization through Intramolecular Hydride Transfer
Author(s) -
Haibach Michael C.,
Seidel Daniel
Publication year - 2014
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201306489
Subject(s) - intramolecular force , hydride , surface modification , realization (probability) , chemistry , ideal (ethics) , redox , bond , combinatorial chemistry , computational chemistry , nanotechnology , materials science , stereochemistry , organic chemistry , philosophy , metal , mathematics , business , epistemology , statistics , finance
Known for over a century, reactions that involve intramolecular hydride‐transfer events have experienced a recent resurgence. Undoubtedly responsible for the increased interest in this research area is the realization that hydride shifts represent an attractive avenue for CH bond functionalization. The redox‐neutral nature of these complexity‐enhancing transformations makes them ideal for sustainable reaction development. This Review summarizes recent progress in this field while highlighting key historical contributions.