A Tandem Isomerization/Prins Strategy: Iridium(III)/Brønsted Acid Cooperative Catalysis | Zendy

Lombardo Vince M. | Zendy; Thomas Christopher D. | Zendy; Scheidt Karl A. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Tandem Isomerization/Prins Strategy: Iridium(III)/Brønsted Acid Cooperative Catalysis

Author(s) -

Lombardo Vince M.,

Thomas Christopher D.,

Scheidt Karl A.

Publication year - 2013

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201306462

Subject(s) - isomerization , iridium , protonation , cationic polymerization , catalysis , tandem , chemistry , brønsted–lowry acid–base theory , combinatorial chemistry , organic chemistry , materials science , ion , composite material

Working together : A mild and efficient isomerization/protonation sequence generates pyran‐fused indoles by cooperative catalysis between cationic iridium(III) and Bi(OTf) 3 . Three distinct cyclization manifolds lead to the corresponding bioactive scaffolds in good yields. In addition, N‐substituted indoles can be synthesized enantioselectively in the presence of a chiral phosphate.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research