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Rhodium(III)‐Catalyzed Azidation and Nitration of Arenes by CH Activation
Author(s) -
Xie Fang,
Qi Zisong,
Li Xingwei
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201305902
Subject(s) - hypervalent molecule , chemistry , nitration , sodium azide , combinatorial chemistry , iodine , catalysis , pyridine , pyrazole , functional group , rhodium , pyrimidine , hydroxylamine , computer science , organic chemistry , stereochemistry , polymer
Getting a handle on it : In the chelation‐assisted title reactions in the presence of a hypervalent iodine oxidant, sodium azide and sodium nitrite served as readily available nitrogen sources, and pyridine, pyrimidine, and pyrazole substituents were efficient directing groups (DGs; see scheme; Cp*=C 5 Me 5 ). The synthetic utility of the azidation products was demonstrated in subsequent functional‐group transformations.