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A “Dial‐A‐Receptor” Dynamic Combinatorial Library
Author(s) -
Hamieh Saleh,
Saggiomo Vittorio,
Nowak Piotr,
Mattia Elio,
Ludlow R. Frederick,
Otto Sijbren
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201305744
Subject(s) - computer science , receptor , service (business) , world wide web , range (aeronautics) , class (philosophy) , library science , information retrieval , chemistry , artificial intelligence , business , biochemistry , engineering , marketing , aerospace engineering
Making receptors to order : A small dynamic combinatorial library (DCL), formed from two dithiols in water, provides a continuous range of six receptors of different sizes. The majority of the 30 tested amines and ammonium ions amplified receptors from this library, thus spanning the complete receptor‐size range and showing that this DCL provides a generic platform for the development of receptors for this important class of compounds.