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Structure Elucidation of Host–Guest Complexes of Tartaric and Malic Acids by Quasi‐Racemic Crystallography
Author(s) -
Lautrette Guillaume,
Kauffmann Brice,
Ferrand Yann,
Aube Christophe,
Chandramouli Nagula,
Dubreuil Didier,
Huc Ivan
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201305364
Subject(s) - foldamer , enantiomer , tartaric acid , diastereomer , malic acid , chemistry , stereochemistry , organic chemistry , citric acid
Racemic on the outside, but not inside : Aromatic‐foldamer hosts are enantiomers and as such prefer to co‐crystallize even though the guests (e.g. L ‐tartaric acid, see picture) in each host are not present as enantiomers. This behavior allows a one‐step structure elucidation of diastereomeric and quasi‐racemic structures in the solid state.