Premium
Chemoselective Oxidative C(CO)C(methyl) Bond Cleavage of Methyl Ketones to Aldehydes Catalyzed by CuI with Molecular Oxygen
Author(s) -
Zhang Lin,
Bi Xihe,
Guan Xiaoxue,
Li Xingqi,
Liu Qun,
Barry BadruDeen,
Liao Peiqiu
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201305010
Subject(s) - catalysis , chemistry , molecular oxygen , oxygen , bond cleavage , oxidative phosphorylation , oxidative cleavage , medicinal chemistry , cleavage (geology) , methyl ketone , photochemistry , organic chemistry , materials science , biochemistry , fracture (geology) , composite material
Aldehyde Termination : A novel copper‐catalyzed transformation from methyl ketones into aldehydes has been accomplished. This method is applicable to a wide range of aromatic and aliphatic methyl ketones and chemoselectively produces aldehydes, accompanied by the release of hydrogen (H 2 ) and carbon dioxide (CO 2 ) as by‐products.