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Selective Reduction of Amides to Amines by Boronic Acid Catalyzed Hydrosilylation
Author(s) -
Li Yuehui,
Molina de La Torre Jesús A.,
Grabow Kathleen,
Bentrup Ursula,
Junge Kathrin,
Zhou Shaolin,
Brückner Angelika,
Beller Matthias
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304495
Subject(s) - benzothiophene , hydrosilylation , chemistry , boronic acid , organic chemistry , primary (astronomy) , functional group , catalysis , selective reduction , reduction (mathematics) , combinatorial chemistry , geometry , mathematics , physics , polymer , astronomy , thiophene
Not a ‘B'ore! Benzothiophene‐based boronic acids catalyze the reduction of tertiary, secondary, and primary amides in the presence of a hydrosilane. The reaction demonstrates good functional‐group tolerance.