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CH Alkenylation of Azoles with Enols and Esters by Nickel Catalysis
Author(s) -
Meng Lingkui,
Kamada Yuko,
Muto Kei,
Yamaguchi Junichiro,
Itami Kenichiro
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304492
Subject(s) - azole , chemistry , catalysis , combinatorial chemistry , computer science , organic chemistry , medicine , antifungal , dermatology
Rather u(Ni)que : Two new CH alkenylation reactions, that is CH/CO alkenylation and decarbonylative CH alkenylation, of azoles are uniquely catalyzed by Ni/dcype. These azole alkenylation reactions are successfully applied to the convergent formal synthesis of siphonazole B.