Premium
CH Alkenylation of Azoles with Enols and Esters by Nickel Catalysis
Author(s) -
Meng Lingkui,
Kamada Yuko,
Muto Kei,
Yamaguchi Junichiro,
Itami Kenichiro
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304492
Subject(s) - azole , chemistry , catalysis , combinatorial chemistry , computer science , organic chemistry , medicine , antifungal , dermatology
Rather u(Ni)que : Two new CH alkenylation reactions, that is CH/CO alkenylation and decarbonylative CH alkenylation, of azoles are uniquely catalyzed by Ni/dcype. These azole alkenylation reactions are successfully applied to the convergent formal synthesis of siphonazole B.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom