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Rhodium‐Catalyzed Oxidative Annulation of Sulfoximines and Alkynes as an Approach to 1,2‐Benzothiazines
Author(s) -
Dong Wanrong,
Wang Long,
Parthasarathy Kanniyappan,
Pan Fangfang,
Bolm Carsten
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304456
Subject(s) - annulation , rhodium , catalysis , chemistry , oxidative phosphorylation , molecular oxygen , oxygen , sequence (biology) , combinatorial chemistry , medicinal chemistry , organic chemistry , biochemistry
Revitalization by oxygen : A rhodium(III)‐catalyzed oxidative CH/NH activation/annulation sequence provided access to a variety of substituted 1,2‐benzothiazine derivatives from readily available N H‐sulfoximines and alkynes (see scheme; Cp*=C 5 Me 5 ). The oxidation system consisted of molecular oxygen in combination with a catalytic amount of Fe(OAc) 2 .