Premium
Inside Cover: Stereoselective Rearrangements with Chiral Hypervalent Iodine Reagents (Angew. Chem. Int. Ed. 27/2013)
Author(s) -
Farid Umar,
Malmedy Florence,
Claveau Romain,
Albers Lena,
Wirth Thomas
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304229
Subject(s) - hypervalent molecule , reagent , iodine , stereoselectivity , chemistry , combinatorial chemistry , salt (chemistry) , organic chemistry , stereochemistry , medicinal chemistry , catalysis
Iodine has made a long journey from being a table salt additive to the key element in efficient chiral reagents. In their Communication on page 7018 ff. T. Wirth and co‐workers describe the utilization of such reagents in stereoselective oxidative rearrangements of alkenes. For the first time, rearrangements to α‐arylated ketones can be performed in high enantioselectivities using chiral hypervalent iodine reagents based on lactic acid.