Hydrophenoxylation of Alkynes by Cooperative Gold Catalysis | Zendy

Oonishi Yoshihiro | Zendy; GómezSuárez Adrián | Zendy; Martin Anthony R. | Zendy; Nolan Steven P. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Hydrophenoxylation of Alkynes by Cooperative Gold Catalysis

Author(s) -

Oonishi Yoshihiro,

GómezSuárez Adrián,

Martin Anthony R.,

Nolan Steven P.

Publication year - 2013

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201304182

Subject(s) - carbene , lewis acids and bases , stereospecificity , chemistry , catalysis , aryl , base (topology) , brønsted–lowry acid–base theory , medicinal chemistry , reaction mechanism , combinatorial chemistry , organic chemistry , polymer chemistry , alkyl , mathematical analysis , mathematics

Double impact : The title method gives aryl vinyl ethers in high yields, short reaction times, Z ‐stereospecificity, and good regioselectivities. Insights into the reaction mechanism highlight the role of [{Au(NHC)} 2 (μ‐OH)][BF 4 ] (NHC=N‐heterocyclic carbene) as both a Lewis acid, [Au(NHC)][BF 4 ], and a Brønsted base, [Au(NHC)(OH)], thereby generating a synergistic effect between the two gold moieties.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research