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Bismuth(V)‐Mediated Thioglycoside Activation
Author(s) -
Goswami Manibarsha,
Ellern Arkady,
Pohl Nicola L. B.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201304099
Subject(s) - bismuth , chemistry , combinatorial chemistry , nanotechnology , stereochemistry , materials science , organic chemistry
A straightforward method utilizing a bismuth(V) compound was developed for the activation of thiopropylglycosides for coupling to various acceptors; good to excellent yields were obtained without applying additional additives/co‐promoters. The method does not require low temperatures, is applicable to a wide variety of carbohydrates, and tolerates different functional groups including alkenes.