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Micropatterned Photodegradable Hydrogels for the Sorting of Microbeads and Cells
Author(s) -
Siltanen Christian,
Shin DongSik,
Sutcliffe Julie,
Revzin Alexander
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303965
Subject(s) - ethylene glycol , sorting , self healing hydrogels , nanotechnology , computer science , micropatterning , sort , lithography , chemistry , materials science , information retrieval , polymer chemistry , organic chemistry , programming language , optoelectronics
Sorted out : Soft‐lithography micropatterning of a photodegradable poly(ethylene glycol) hydrogel was utilized to sort cell‐bound microbeads. Biofunctionalized microbeads were patterned, screened for cell binding activity, and isolated from arrays by UV irradiation. The technique is a simple approach for sorting and downstream processing of cultured cells.