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Palladium‐Catalyzed Reductive Carbonylation of Aryl Halides with N ‐Formylsaccharin as a CO Source
Author(s) -
Ueda Tsuyoshi,
Konishi Hideyuki,
Manabe Kei
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303926
Subject(s) - carbonylation , aryl , halide , catalysis , butane , palladium , chemistry , medicinal chemistry , organic chemistry , carbon monoxide , alkyl
Easy peasy : The title reaction employs N ‐formylsaccharin, which is an easily accessible crystalline compound, as an effective CO source. The reactions proceed with a small excess of the CO source at moderate temperatures and were successfully applied to a wide range of aryl bromides. DMF= N , N ‐dimethylformamide, dppb=1,4‐bis‐(diphenylphosphino)butane.