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The Sixteenth Iron in the Nitrogenase MoFe Protein
Author(s) -
Zhang Limei,
Kaiser Jens T.,
Meloni Gabriele,
Yang KunYun,
Spatzal Thomas,
Andrade Susana L. A.,
Einsle Oliver,
Howard James B.,
Rees Douglas C.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303877
Subject(s) - nitrogenase , sequence (biology) , chemistry , crystallography , biochemistry , nitrogen fixation , organic chemistry , nitrogen
Another iron in the fire : X‐ray anomalous diffraction studies on the nitrogenase MoFe protein show the presence of a mononuclear iron site, designated as Fe16, which was previously identified as either Ca 2+ or Mg 2+ . The position of the absorption edge indicates that this site is in the oxidation state +2. The high sequence conservation of the residues coordinated to Fe16 emphasizes the potential importance of the site in nitrogenase.