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pH‐Switchable Ampholytic Supramolecular Copolymers
Author(s) -
Frisch Hendrik,
Unsleber Jan Patrick,
Lüdeker David,
Peterlechner Martin,
Brunklaus Gunther,
Waller Mark,
Besenius Pol
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303810
Subject(s) - supramolecular chemistry , cationic polymerization , copolymer , monomer , amphiphile , polymerization , nanotechnology , self assembly , computer science , value (mathematics) , materials science , combinatorial chemistry , chemistry , polymer chemistry , organic chemistry , molecule , polymer , machine learning
β‐sheet‐encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self‐assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on‐off polymerization in response to pH triggers. The cooperative supramolecular self‐assembly process is switched on at a physiologically relevant pH value and can be switched off by increasing or decreasing the pH value.