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Copper‐Catalyzed Dehydrogenative Coupling of Arenes with Alcohols
Author(s) -
Bhadra Sukalyan,
Matheis Christian,
Katayev Dmitry,
Gooßen Lukas J.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303702
Subject(s) - catalysis , chemistry , intermolecular force , aryl , alkyl , copper , coupling (piping) , organic chemistry , oxidative coupling of methane , polymer chemistry , combinatorial chemistry , materials science , molecule , metallurgy
What a couple! Arenes functionalized with donating groups undergo oxidative dehydrogenative coupling with alcohols in the presence of a copper/silver catalyst system. This intermolecular CH alkoxylation provides a convenient synthetic route to the important class of aryl ethers. The catalyst system also allows the alkoxylation of benzylic CH groups with formation of benzyl alkyl ethers.