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Self‐Assembly of DNA Origami and Single‐Stranded Tile Structures at Room Temperature
Author(s) -
Zhang Zhao,
Song Jie,
Besenbacher Flemming,
Dong Mingdong,
Gothelf Kurt V.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303611
Subject(s) - tile , dna origami , ribbon , nanotechnology , computer science , loop mediated isothermal amplification , isothermal process , dna , materials science , nanostructure , chemistry , physics , biochemistry , composite material , thermodynamics
Efficient self‐assembly : Self‐assembly of DNA nanostructures at room temperature was achieved by incubating the component strands in the presence of a denaturing agent (30–40% formamide). This isothermal method is efficient for assembly of both DNA origami (purple, see scheme) and single‐stranded tile (SST, blue) structures, as well as an SST ribbon growing on an origami template.