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8‐Aminoquinoline: A Powerful Directing Group in Metal‐Catalyzed Direct Functionalization of CH Bonds
Author(s) -
Corbet Matthieu,
De Campo Floryan
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303556
Subject(s) - surface modification , chelation , group (periodic table) , combinatorial chemistry , metal , chemistry , catalysis , functional group , organic chemistry , polymer
Chelate me if you can : Over the last decade, strategies for the functionalization of both C sp 2H and C sp 3H bonds have witnessed an increasing use of a simple, yet powerful directing group, 8‐aminoquinoline (in blue). This auxiliary is very efficient in a wide range of metal‐mediated reactions, and can be readily removed to afford the desired carboxylic acids or corresponding derivatives.