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In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous‐Flow Transfer Hydrogenation of Olefins
Author(s) -
Pieber Bartholomäus,
Martinez Sabrina Teixeira,
Cantillo David,
Kappe C. Oliver
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303528
Subject(s) - hydrazine (antidepressant) , diimide , catalysis , computer science , in situ , process (computing) , chemistry , process engineering , combinatorial chemistry , materials science , organic chemistry , operating system , molecule , engineering , perylene , chromatography
No catalyst required! A highly efficient, catalyst‐free process to generate diimide in situ from hydrazine monohydrate and molecular oxygen for the selective reduction of alkenes has been developed. The use of a gas–liquid segmented flow system allowed safe operating conditions and dramatically enhanced this atom‐economical reaction, resulting in short processing times.