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A Mild, One‐Pot Stadler–Ziegler Synthesis of Arylsulfides Facilitated by Photoredox Catalysis in Batch and Continuous‐Flow
Author(s) -
Wang Xiao,
Cuny Gregory D.,
Noël Timothy
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303483
Subject(s) - microreactor , photoredox catalysis , aryl , catalysis , continuous flow , alkyl , chemistry , visible spectrum , combinatorial chemistry , organic chemistry , photochemistry , chemical engineering , materials science , photocatalysis , biochemical engineering , engineering , optoelectronics
Visible advance : A mild, one‐pot Stadler–Ziegler process for CS bond formation has been developed. The method employs the photoredox catalyst [Ru(bpy) 3 Cl 2 ]⋅6 H 2 O irradiated with visible light. A variety of aryl–alkyl and diaryl sulfides were prepared from readily available arylamines and aryl/alkylthiols in good yields. The use of a photo microreactor led to a significant improvement with respect to safety and efficiency.