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Semiconducting Polymer Nanoprobe for In Vivo Imaging of Reactive Oxygen and Nitrogen Species
Author(s) -
Pu Kanyi,
Shuhendler Adam J.,
Rao Jianghong
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201303420
Subject(s) - nanoprobe , förster resonance energy transfer , reactive oxygen species , oxygen , polymer , inert , reactive nitrogen species , fluorescence , in vivo , energy transfer , photochemistry , chemistry , nitrogen , nanotechnology , materials science , nanoparticle , biophysics , biochemistry , chemical physics , organic chemistry , biology , optics , physics , microbiology and biotechnology
Semiconducting polymer nanoparticles are used as a free‐radical inert and light‐harvesting nanoplatform for in vivo molecular imaging of reactive oxygen and nitrogen species (RONS). This nanoprobe permits detection of RONS in the microenvironment of spontaneous bacterial infection (see picture; FRET=fluorescence resonance energy transfer).