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A Two‐Channel Ratiometric Electrochemical Biosensor for In Vivo Monitoring of Copper Ions in a Rat Brain Using Gold Truncated Octahedral Microcages
Author(s) -
Chai Xiaolan,
Zhou Xinguang,
Zhu Anwei,
Zhang Limin,
Qin Yao,
Shi Guoyue,
Tian Yang
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302958
Subject(s) - microelectrode , biosensor , in vivo , electrochemistry , electrode , copper , ion , metal ions in aqueous solution , octahedron , chemistry , materials science , combinatorial chemistry , nanotechnology , inorganic chemistry , organic chemistry , biology , microbiology and biotechnology
Brain chemistry : A biosensor has been developed for in vivo determination of copper ions in a rat brain by using gold truncated octahedral microcages. The significant analytical performance of the present biosensor, as well as the properties of a carbon fiber microelectrode have provided a direct and reliable approach for monitoring cerebral metal ions (W.E.=working electrode; see picture).