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Polymer Nanomicelles for Efficient Mucus Delivery and Antigen‐Specific High Mucosal Immunity
Author(s) -
Noh YoungWoock,
Hong Ji Hyun,
Shim SangMu,
Park Hye Sun,
Bae Hee Ho,
Ryu Eun Kyoung,
Hwang Jung Hwan,
Lee ChulHo,
Cho Seong Hun,
Sung MoonHee,
Poo Haryoung,
Lim Yong Taik
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302881
Subject(s) - mucosal immunity , immunity , mucus , antigen , immune system , immunology , computer science , medicine , computational biology , biology , ecology
Micelles for mucosal immunity: A mucosal vaccine system based on γ‐PGA nanomicelles and viral antigens was synthesized. The intranasal administration of the vaccine system induces a high immune response both in the humoral and cellular immunity (see picture).