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Supramolecular Assemblies of Amphiphilic L ‐Proline Regulated by Compressed CO 2 as a Recyclable Organocatalyst for the Asymmetric Aldol Reaction
Author(s) -
Qin Long,
Zhang Li,
Jin Qingxian,
Zhang Jianling,
Han Buxing,
Liu Minghua
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302662
Subject(s) - supramolecular chemistry , aldol reaction , amphiphile , proline , chemistry , organocatalysis , computer science , catalysis , combinatorial chemistry , organic chemistry , enantioselective synthesis , molecule , biochemistry , polymer , copolymer , amino acid
Compressed CO 2 triggers the formation of amphiphilic proline supramolecular assemblies in water, which catalyze the asymmetric aldol reaction without any additives. Compressed CO 2 can dynamically regulate the size of the assemblies and subsequently the catalyst activity and selectivity. Furthermore, CO 2 provides the merit of easy separation and purification, making the process sustainable and recyclable.