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Modifying Alkylzinc Reactivity with 2,2′‐Dipyridylamide: Activation of t BuZn Bonds for para ‐Alkylation of Benzophenone
Author(s) -
Armstrong David R.,
Garden Jennifer A.,
Kennedy Alan R.,
Mulvey Robert E.,
Robertson Stuart D.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302426
Subject(s) - chemistry , library science , benzophenone , organic chemistry , computer science
Undercover agent : Masquerading as a simple donor‐acceptor complex ( 1 ), sodium amide substoichiometrically activates t Bu 2 Zn for the challenging 1,6‐addition of a tert‐ butyl group to benzophenone. In contrast, the nonactivated t Bu 2 Zn is ineffectual.
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