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Total Synthesis and Stereochemical Assignment of Baringolin
Author(s) -
JustBaringo Xavier,
Bruno Paolo,
Ottesen Lars K.,
Cañedo Librada M.,
Albericio Fernando,
Álvarez Mercedes
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302372
Subject(s) - total synthesis , stereochemistry , chemistry
The thiopeptide antibiotic baringolin has been synthesized, and its structure and stereochemistry have been confirmed. The use of a strategy based on palladium‐catalyzed cross‐couplings permitted a modular construction of this natural product.