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Design and Synthesis of a Universal Antigen to Detect Brucellosis
Author(s) -
Guiard Julie,
Paszkiewicz Eugenia,
Sadowska Joanna,
Bundle David R.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302303
Subject(s) - brucella , brucellosis , computer science , antigen , service (business) , computational biology , world wide web , virology , biology , immunology , business , marketing
Upgrading diagnostics : A universal antigen has been prepared for the detection of brucellosis caused by any Brucella species that express a smooth lipopolysaccharide. This nonasaccharide, which encompasses Brucella A‐ and M‐antigenic determinants, is uniquely available only by chemical synthesis.