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Near‐Infrared‐ and pH‐Responsive System for Reversible Cell Adhesion using Graphene/Gold Nanorods Functionalized with i‐Motif DNA
Author(s) -
Li Wen,
Wang Jiasi,
Ren Jinsong,
Qu Xiaogang
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201302048
Subject(s) - nanorod , linker , graphene , substrate (aquarium) , dna , adhesion , materials science , infrared , nanotechnology , chemical engineering , chemistry , biochemistry , optics , composite material , engineering , geology , oceanography , physics , computer science , operating system
It′s a keeper! A dual near‐infrared (NIR)‐ and pH‐responsive system for the controlled catch‐and‐release of cells was achieved using graphene/Au nanorods as a substrate and double‐stranded DNA as a switchable linker for cell immobilization (see scheme). This substrate was shown to respond to cycles of NIR light and changes in pH, and released undamaged cells from the surface.