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Asymmetric Ruthenium‐Catalyzed Hydrogenation of 2‐ and 2,9‐Substituted 1,10‐Phenanthrolines
Author(s) -
Wang Tianli,
Chen Fei,
Qin Jie,
He YanMei,
Fan QingHua
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201301830
Subject(s) - ruthenium , cationic polymerization , catalysis , chemistry , medicinal chemistry , asymmetric hydrogenation , diamine , phenanthroline , enantioselective synthesis , polymer chemistry , combinatorial chemistry , organic chemistry
A ‘Phen'atic : The title reaction proceeds in the presence of the chiral cationic ruthenium diamine catalyst ( R , R )‐ 1 (Tf=trifluoromethanesulfonyl, Ts=4‐toluenesulfonyl). Both chiral 1,2,3,4‐tetrahydro‐ and 1,2,3,4,7,8,9,10‐octahydro‐1,10‐ phenanthroline derivatives could be obtained in high yields with excellent enantio‐ and diastereoselectivity.