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A Supramolecular Peptide Synthesizer
Author(s) -
BertranVicente Jordi,
Hackenberger Christian P. R.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201301825
Subject(s) - peptide , rotaxane , assembly line , supramolecular chemistry , sequence (biology) , combinatorial chemistry , computational biology , chemistry , nanotechnology , computer science , stereochemistry , biochemistry , engineering , materials science , biology , molecule , organic chemistry , mechanical engineering
Line up for synthesis! In a recent report the Leigh group described a rotaxane‐based setup for the sequence‐specific synthesis of small peptides, which runs automatically once started. This molecular machine combines elements from both chemical and biochemical peptide (bio‐)syntheses, which are discussed in this Highlight.