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Gold Catalysis: Highly Functionalized Cyclopentadienes Prepared by Intermolecular Cyclization of Ynamides and Propargylic Carboxylates
Author(s) -
Rettenmeier Eva,
Schuster Andreas M.,
Rudolph Matthias,
Rominger Frank,
Gade Christoph A.,
Hashmi A. Stephen K.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201301382
Subject(s) - carbenoid , chemistry , electrophile , cyclopentadiene , silylation , combinatorial chemistry , organic chemistry , catalysis , rhodium
When an ynamide meets a gold carbenoid : Highly electrophilic gold carbenoids available from propargylic esters by means of 1,2‐acyloxy migration open up new reaction pathways for ynamide gold chemistry. In this way highly functionalized cyclopentadiene derivatives become accessible (see scheme; EWG=electron‐withdrawing group).