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A Short Enantioselective Total Synthesis of (−)‐Englerin A
Author(s) -
Zahel Martin,
Keßberg Anton,
Metz Peter
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201301247
Subject(s) - enantioselective synthesis , computer science , closing (real estate) , metathesis , service (business) , world wide web , dual (grammatical number) , chemistry , catalysis , organic chemistry , business , philosophy , linguistics , polymer , finance , marketing , polymerization
Selective oxidations of dienone 2 as well as a ring‐closing metathesis to give the hydroazulene framework enabled the 12‐step preparation of title compound 1 from (−)‐photocitral A ( 3 ), which is in turn rapidly available from (−)‐isopulegol through dual catalysis.