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Cover Picture: Palladium‐Catalyzed Oxidative Cross‐Coupling between Heterocycles and Terminal Alkynes with Low Catalyst Loading (Angew. Chem. Int. Ed. 13/2013)
Author(s) -
Jie Xiaoming,
Shang Yaping,
Hu Peng,
Su Weiping
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201301067
Subject(s) - palladium , catalysis , alkynylation , selectivity , terminal (telecommunication) , chemistry , cover (algebra) , coupling (piping) , medicinal chemistry , annulation , polymer chemistry , materials science , combinatorial chemistry , organic chemistry , metallurgy , computer science , engineering , mechanical engineering , telecommunications
The direct alkynylation of electron‐rich aromatic heterocycles with terminal alkynes was accomplished in high yields and good selectivity when using a low loading of palladium catalyst, as described by W. Su and co‐workers in their Communication on page 3630 ff. A high loading of palladium catalyst led to poor yields because of the undesired homocoupling of alkynes.
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