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Copper Salts as Additives in Gold(I)‐Catalyzed Reactions
Author(s) -
Guérinot Amandine,
Fang Weizhen,
Sircoglou Marie,
Bour Christophe,
BezzenineLafollée Sophie,
Gandon Vincent
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201300600
Subject(s) - reactivity (psychology) , catalysis , copper , metathesis , silver salts , salt metathesis reaction , chemistry , ion , inorganic chemistry , combinatorial chemistry , polymer chemistry , organic chemistry , polymerization , medicine , alternative medicine , pathology , polymer
The right combination : Cu I and Cu II salts can advantageously replace silver additives in Au I ‐catalyzed reactions. On the basis of reactivity studies and NMR experiments, it is believed that anion metathesis between CuY n (Y=OTf, BF 4 , PF 6 , SbF 6 ) and [R 3 PAuCl] takes place to give [R 3 PAu]Y. As this process is slow, there is no fast decay of the active species, thus allowing large‐scale reactions, even at high temperatures, with low loadings of the gold complex.