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Recyclable Mitsunobu Reagents: Catalytic Mitsunobu Reactions with an Iron Catalyst and Atmospheric Oxygen
Author(s) -
Hirose Daisuke,
Taniguchi Tsuyoshi,
Ishibashi Hiroyuki
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201300153
Subject(s) - catalysis , reagent , hydrazine (antidepressant) , chemistry , triphenylphosphine , mitsunobu reaction , atmospheric oxygen , molecular sieve , organic chemistry , combinatorial chemistry , oxygen , chromatography
Aerobic recycling : A catalytic amount of a hydrazine reagent is sufficient to promote Mitsunobu reactions in the presence of triphenylphosphine, an iron catalyst, and air. The active form of the catalyst, an azo species, can be readily generated by iron‐catalyzed aerobic oxidation. MS=molecular sieves, Pc=phthalocyanine.