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Determination of Labile Chiral Supramolecular Ion Pairs by Chromatographic NMR Spectroscopy
Author(s) -
Reddy G. N. Manjunatha,
BallesterosGarrido Rafael,
Lacour Jérôme,
Caldarelli Stefano
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209616
Subject(s) - supramolecular chemistry , chemistry , spectroscopy , ion , nuclear magnetic resonance spectroscopy , characterization (materials science) , diffusion , chromatography , analytical chemistry (journal) , organic chemistry , nanotechnology , materials science , molecule , physics , quantum mechanics , thermodynamics
Chiral recognition : Silica‐enhanced NMR diffusometry can distinguish the signals of diastereoisomeric mixtures of supramolecular ion pairs (see picture; DOSY=diffusion‐ordered spectroscopy). The experiment has a shorter timescale than liquid chromatography, thus allowing an easier characterization of species that are even configurationally labile on the minutes timescale.