Premium
Ketene Three‐Component Reaction: A Metal‐Free Multicomponent Approach to Stereodefined Captodative Olefins
Author(s) -
Basso Andrea,
Banfi Luca,
Garbarino Silvia,
Riva Renata
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209399
Subject(s) - synthon , ketene , chemistry , olefin fiber , component (thermodynamics) , organic chemistry , combinatorial chemistry , catalysis , physics , thermodynamics
Three in the spotlight : Irradiation promotes a general, three‐component reaction between diazoketones, carboxylic acids, and isocyanides. The highly functionalized captodative olefin products of this reaction are versatile synthons for organic synthesis.