Premium
Design, Synthesis, and Biological Evaluation of Truncated Superstolide A
Author(s) -
Chen Lei,
Riaz Ahmed Kausar Begam,
Huang Peng,
Jin Zhendong
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209300
Subject(s) - computer science , product (mathematics) , service (business) , information retrieval , world wide web , mathematics , business , geometry , marketing
By design : A truncated superstolide A, a simplified analogue of the potent anticancer marine macrolide superstolide A, was designed and successfully synthesized by a highly efficient and convergent approach. The biological evaluation showed that this compound maintains the potent anticancer activity of the original natural product superstolide A.