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A Cationic High‐Valent Cp*Co III Complex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed CH Bond Activation
Author(s) -
Yoshino Tatsuhiko,
Ikemoto Hideya,
Matsunaga Shigeki,
Kanai Motomu
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209226
Subject(s) - electrophile , nucleophile , cationic polymerization , chemistry , medicinal chemistry , catalysis , reagent , aryl , amide , organometallic chemistry , nucleophilic addition , combinatorial chemistry , stereochemistry , polymer chemistry , organic chemistry , alkyl
Active without activation : In an inexpensive and atom‐economical approach to CH bond functionalization, a cationic Co III complex (see scheme) was used to generate nucleophilic organometallic species in situ without additional activating reagents. Under these conditions, aryl CH bonds underwent efficient addition to polar electrophiles, including α,β‐unsaturated N ‐acyl pyrroles as β‐substituted ester and amide surrogates.