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Synthesis of Single‐Chain Sugar Arrays
Author(s) -
Baradel Nathalie,
Fort Sébastien,
Halila Sami,
Badi Nezha,
Lutz JeanFrançois
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209052
Subject(s) - hexose , chain (unit) , mannose , sequence (biology) , galactose , polystyrene , chemistry , sugar , polymer , polymerization , polymer chemistry , biochemistry , organic chemistry , enzyme , physics , astronomy
Polymers that toe the line : Well‐defined linear polystyrene chains containing precisely positioned hexose moieties (mannose, galactose, and N ‐acetylglucosamine) were synthesized by a sequence‐controlled polymerization approach followed by a series of site‐selective modification steps. Such multifunctional single‐chain hexose arrays associate specifically with complementary lectins (see picture).