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Copper‐Catalyzed Addition of Nucleophilic Silicon to Aldehydes
Author(s) -
Cirriez Virginie,
Rasson Corentin,
Hermant Thomas,
Petrignet Julien,
Díaz Álvarez Jesús,
Robeyns Koen,
Riant Olivier
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201209020
Subject(s) - silane , enantioselective synthesis , aldehyde , silylation , copper , nucleophile , chemistry , silicon , catalysis , silanes , organic chemistry , polymer chemistry , combinatorial chemistry
How to train your silane : A new family of chiral copper(I) complexes that bear a bifluoride counteranion were prepared and used in the first example of the enantioselective transfer of a silyl group to an aldehyde. This procedure provides fast access to non‐racemic α‐hydroxysilanes in high enantioselectivities.