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Copper‐Catalyzed Oxidative Coupling of Alkenes with Aldehydes: Direct Access to α,β‐Unsaturated Ketones
Author(s) -
Wang Jing,
Liu Chao,
Yuan Jiwen,
Lei Aiwen
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208920
Subject(s) - oxidative coupling of methane , catalysis , chemistry , copper , alkene , oxidative phosphorylation , coupling (piping) , electron transfer , coupling reaction , organic chemistry , photochemistry , materials science , biochemistry , metallurgy
Let's get radical : The first copper‐catalyzed oxidative coupling of alkenes and aldehydes was developed. Various aldehydes were utilized as substrates to construct α,β‐unsaturated ketones. A preliminary mechanistic study indicated that this reaction is likely to proceed through a single‐electron transfer.